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Inside these cells, AAS can biotransform into various metabolites or bind to their cognate receptor: the androgen receptor. AAS as well as their metabolites can cause Negative effects including acne vulgaris, hypertension, hepatotoxicity, dyslipidemia, testosterone deficiency, erectile dysfunction, gynecomastia, and cardiomyopathy. In which applica… Read More
A further analyze confirmed a task of apoptosis in AAS-linked hurt. Androgens may improve the expression of profibrotic cytokines like TGF-b in mice kidneys, bringing about the activation in the apoptotic procedure and also the marketing of focal segmental glomerulosclerosis. Moreover, environmental and inflammation stress may lead to proteotoxic h… Read More
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